|
KMID : 1123920100240020284
|
|
Korean Journal of Oriental Physiology and Pathology
2010 Volume.24 No. 2 p.284 ~ p.289
|
|
|
( Effect of Artemisiae Argi Folium Fermented with Sacchromyces Cerevisiae on Viability of Human Hepatocyte Treated with Toxicants )
|
|
Park Wan-Su
|
|
|
Abstract
|
|
|
|
The purpose of this study is to investigate the effect of water extract from Artemisiae Argi Folium Fermented with Sacchromyces cerevisiae (AFS) on viability of human hepatocyte HepG2 cells treated with hepatotoxicants such as EtOH, gallic acid, nicotine, acetaminophen, acetaldehyde, and lipopolysaccharide. AFS (0~400 ug/mL) was treated with EtOH, gallic acid, nicotine, acetaminophen, acetaldehyde, and lipopolysaccharide. And the viability of HepG2 cells was measured by MTT assay. AFS showed to increase significantly viabilities of HepG2 cells compared with hepatotoxicants (EtOH, gallic acid, nicotine, acetaminophen, and lipopolysaccharide) only (p<0.05). AFS could be supposed to have the hepatoprotective effect against hepatotoxicants such as gallic acid, EtOH, nicotine, acetaminophen, and lipopolysaccharide.
|
|
|
KEYWORD
|
|
|
hepatocyte, sacchromyces cerevisiae, artemisiae argi folium, fermentation, cell viability
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|